This study examined the association of inflammatory markers in serum or plasma with prevalent MCI and MCI subtypes in a population-based sample. Olmsted County, MN, residents aged 70—89 years on October 1, , were evaluated using the Clinical Dementia Rating Scale, a neurological evaluation, and neuropsychological testing. Information ascertained for each participant was reviewed by an expert panel of neuropsychologists, physicians, and nurses, and a diagnosis of normal cognition, MCI, or dementia was made by consensus. No association was observed with the other inflammatory markers. These findings suggest an involvement of inflammation in the pathogenesis of MCI. Adiponectin is an anti-diabetic and anti-inflammatory hormone [ 6 — 8 ], and low levels have been associated with vascular disease.

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Background: The population of oldest old is increasing, but the prevalence of cognitive impairment is not well characterized in this group.

Objectives: To determine the prevalence of mild cognitive impairment MCI , dementia, and their subtypes in oldest old women and to examine whether some groups of oldest old women were more likely to have cognitive impairment. Design: Prospective cohort study.

Main outcome measures: All the women completed a neuropsychological test battery. Dementia and MCI subtypes were determined using standard criteria. Results: The women had a mean age of Amnestic multiple domain and nonamnestic single domain were the most common MCI types, accounting for Cognitive impairment was more frequent in women 90 years or older compared with those 85 to 89 years dementia, Conclusions: In this large sample of oldest old women, Subtypes of dementia and MCI were similar to those in younger populations.

Women in the fastest growing demographic, the oldest old, should be screened for cognitive disorders, especially high-risk groups. This site needs JavaScript to work properly. Please enable it to take advantage of the complete set of features! Clipboard, Search History, and several other advanced features are temporarily unavailable. Search: Search. Advanced Clipboard. Create file Cancel. Email citation To:. Format: Summary Summary text Abstract Abstract text.

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Full-text links Cite Favorites. Abstract Background: The population of oldest old is increasing, but the prevalence of cognitive impairment is not well characterized in this group. Figure 1 13 Prevalence of cognitive impairment MCI and dementia among sub-groups of oldest old women.

Prevalence of cognitive impairment MCI and dementia among sub-groups of oldest old women. See this image and copyright information in PMC. Similar articles Conversion of mild cognitive impairment to dementia in elderly subjects: a preliminary study in a memory and cognitive disorder unit. Maioli F, et al.

Arch Gerontol Geriatr. PMID: Incidence of dementia in oldest-old with amnestic MCI and other cognitive impairments. Peltz CB, et al. Epub Nov 9. Outcomes of mild cognitive impairment by definition: a population study.

Ganguli M, et al. Arch Neurol. Jonker C, Comijs HC. Jonker C, et al. Tijdschr Gerontol Geriatr. PMID: Review. Defrancesco M, et al. Show more similar articles See all similar articles. Wang B, et al. J Nutr Health Aging.

Objective napping, cognitive decline, and risk of cognitive impairment in older men. Leng Y, et al. Alzheimers Dement. Epub Jun Bowman GL, et al. Clinical Trial. Huang Y, et al. Commun Biol. An investigation into the prevalence of cognitive impairment and the performance of older adults in Guilan province.

Soleimani R, et al. J Med Life. Show more "Cited by" articles See all "Cited by" articles. Publication types Research Support, N. Research Support, Non-U. Gov't Actions. MeSH terms Aged, 80 and over Actions. Female Actions. Humans Actions. Prevalence Actions. Prospective Studies Actions. Show all 22 grants. Copy Download.


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Mild Cognitive Impairment, Dementia, and Their Subtypes in Oldest Old Women




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