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We'd like to understand how you use our websites in order to improve them. Register your interest. The concept of pharmacological ethnic safety is presented. Drug safety varies for different ethnic groups populations depending on their metabolic status, i. According to the results, drugs exported to monoethnic and multiethnic countries should be thoroughly tested for metabolic safety for ethnic groups with particular drug-metabolism phenotypes.
On the basis of this concept, the ethnic metabolic safety of drugs subjected to phase I biotransformation reactions oxidation and hydrolysis has been theoretically estimated. The dependence of the predisposition to side effects of these drugs on the frequencies of different phenotypes for the types and rates of these two reactions is specially emphasized. This is a preview of subscription content, log in to check access. Rent this article via DeepDyve.
Kalow, W. Google Scholar. Lakin, K. Kholodov, L. Piruzyan, L. Savilov, E. Fedorova, E. Nakamura, K. Relling, M. Rudolfer, M. Idle, J. Woolhouse, N. Evans, D. Oates, N. Mahgoub, A.
Islam, S. Bathum, L. Inaba, T. Vinks, A. Eichelbaum, M. Liss, , p. Mbanefo, C. Playfer, J. Lubin, A. Download references. Reprints and Permissions. Human Physiology 29, — Download citation. Issue Date : March Search SpringerLink Search. Abstract The concept of pharmacological ethnic safety is presented. Kosygina 4, Moscow, , Russia. Semenov Institute of Chemical Physics L. Mikhailovskii Authors L. Piruzyan View author publications. You can also search for this author in PubMed Google Scholar.
View author publications. Rights and permissions Reprints and Permissions. About this article Cite this article Piruzyan, L.
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An opto-isolator also called an optocoupler , photocoupler , or optical isolator is an electronic component that transfers electrical signals between two isolated circuits by using light. A common type of opto-isolator consists of an LED and a phototransistor in the same opaque package. Usually opto-isolators transfer digital on-off signals, but some techniques allow them to be used with analog signals. The value of optically coupling a solid state light emitter to a semiconductor detector for the purpose of electrical isolation was recognized in by Akmenkalns, et al. US patent 3,, Photoresistor-based opto-isolators were introduced in
October General Description. This device is designed specifically as a single package solution for DC to DC converters. Drain-Source Voltage. Gate-Source Voltage. Drain Current.
MMDFS2P102 MOSFET. Datasheet pdf. Equivalent
Pharmacological Ethnic Metabolic Safety: Communication I