Log In Toggle navigation Search. Set Preferences. All HACEK organisms are commensals of the human oropharynx but how they travel to distal sites to cause disease is not fully established. One hypothesis is that they spread hematogenously following introduction into the blood during tooth brushing, dental cleanings, or subsequent to oral diseases such as periodontitis. Most endocarditis is caused by Gram-positive bacteria most commonly Staphylococcus or Streptococcus with a minority caused by Gram-negatives or fungi. A recent multinational study attributed 1.
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Endocardite infecciosa causada por Eikenella corrodens. Oliveira Jr. Relatamos o caso de uma paciente com valva nativa que apresentou endocardite infecciosa causada por Eikenella corrodens. O tratamento foi modificado para ceftriaxone 2 g por dia. Paciente evoluiu com melhora. Na literatura, identificamos dezenove casos de endocardite por Eikenela corrodens. Infective endocarditidis due to unusual or fastidious microorganisms. Mayo Clin Proc ; Mycotic aneurysm of the sinus of valsalva due to Eikenella corrodens bacterial endocarditis.
Cardiology ; APMIS ; Eikenella corrodens infective endocarditis in a previously heathy non-drug user. Landis SJ, Korver J. Eikenella corrodens endocarditis: case report and review of the literatute. Can Med Assoc J ; Optimisation of the prevention and treatment of bacterial endocarditis. Drugs Aging ; Antibiotic treatment of adults with infective endocardites due to streptococci, enterococci, staphylococci, and HACEK microorganisms.
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The HACEK organisms are a group of fastidious Gram-negative bacteria that are an unusual cause of infective endocarditis , which is an inflammation of the heart due to bacterial infection. The bacteria were originally grouped because they were thought to be a significant cause of infective endocarditis, but recent research has shown that they are rare and only responsible for 1. HACEK originally referred to Haemophilus parainfluenzae , Haemophilus aphrophilus , Actinobacillus actinomycetemcomitans , Cardiobacterium hominis , Eikenella corrodens , and Kingella kingae. However, taxonomic rearrangements have changed the A to Aggregatibacter species and the H to Haemophilus species to reflect the recategorization and novel identification of many of the species in these genera. All of these organisms are part of the normal oropharyngeal flora, which grow slowly up to 14 days , prefer a carbon dioxide—enriched atmosphere, and share an enhanced capacity to produce endocardial infections, especially in young children. They have been a frequent cause of culture-negative endocarditis.
Who Are the HACEK Organisms?
Treatment is with antibiotics. The HACEK group of nonmotile, gram-negative bacilli or coccobacilli contains a number of minimally pathogenic, slow-growing, fastidious genera. The group consists of. Haemophilus species H. Aggregatibacter formerly Actinobacillus actinomycetemcomitans , which usually occurs with A.