The "fragility" of the nervous system, especially concerning to its nutrition and metabolism, explains why vitamin deficits are an important cause of neurological pathology. Some deficiency diseases, which can be very severe and irreversible, are still present in our environment; diagnosis, which must be early so as not to delay treatment, can be difficult if we do not have them in mind. In this review we address the most relevant neurological diseases associated with thiamine, folate and cobalamin deficiency, and we focus especially combined subacute degeneration and Wernicke-Korsakoff syndrome. This site needs JavaScript to work properly.

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We'd like to understand how you use our websites in order to improve them. Register your interest. Therapy with B12 leads to improvement in most but to complete recovery in only a few patients. Prognostic indicators in subacute combined degeneration are unknown; therefore, predicting complete recovery of neurologic deficits is challenging. PURPOSE: To identify potential correlates of outcome and to generate hypotheses concerning predictors of complete resolution of neurologic deficits in subacute combined degeneration.

The absence of sensory dermatomal deficit, Romberg, and Babinski signs were associated with a higher complete resolution rate. However, complete resolution only occurs in a small percentage of patients and appears to be associated with factors suggestive of less severe disease at the time of diagnosis. This is a preview of subscription content, log in to check access.

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[Neurological Pathology Associated With Vitamin B Group Deficiency: Thiamine, Folate and Cobalamin]

MRI in the diagnostic and evolutive control of subacute combined degeneration. A case report. Saiz-Mendiguren 1,3 , R. Irimia 2 , E.


Potential outcome factors in subacute combined degeneration

Dementia caused by vitamin B12 deficiency. Report of one case. Cyanocobalamin vitamin B12 deficiency can cause polyneuropathy, myelopathy, blindness, confusion, psychosis and dementia. Nonetheless, its deficiency as the sole cause of dementia is infrequent.

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