KK is an author of a number of references cited in this topic and has developed educational material on Churg-Strauss syndrome for First Consult Elsevier. KK has undertaken contractual research for GlaxoSmithKline utilizing mepolizumab and sirukumab in asthma trials , but received no personal financial gain for this work. Dr Karina Keogh would like to gratefully acknowledge Dr Garvan Kane, a previous contributor to this topic. GK is an author of a number of references cited in this topic. RL has organisational financial interests with funds received for consultation and training on disease assessment in vasculitis for GlaxoSmithKline, Nordic, and Chemocentryx. RL has received personal funds for lectures on vasculitis from Roche and Nippon Kayaku.
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Churg-Strauss syndrome is a rare systemic disease primarily characterized by hypereosinophilia, asthma and vasculitis. The lung is the organ most frequently involved. In the present report, the authors describe a relatively rare finding in this disease - the presence of a pulmonary nodule -, while recalling the main radiological findings and the most relevant differential diagnoses.
Radiol Bras. Pulmonary angiitis and granulomatosis: radiologic-pathologic correlation. Thoracic manifestations of systemic autoimune diseases: radiographic and high-resolution CT findings.
Eosinophilic lung diseases: diagnostic accuracy of thin-section in patients. When to suspect pulmonary vasculitis: radiologic and clinical clues. Imaging of pulmonary vasculitis. Hansell DM. Small-vessel diseases of the lung: CT-pathologic correlates. Katzenstein ALA. Diagnostic features and differential diagnosis of Churg-Strauss syndrome in the lung. A review. Am J Clin Pathol.
Gabriel Lacerda Fernandes. E-mail: lacerda-gabriel hotmail. This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
Services on Demand Journal. Palavras-Chave: Vasculite; Eosinofilia; Asma. Key words: Vasculitis; Eosinophilia; Asthma. Recebido: 08 de Junho de ; Aceito: 22 de Outubro de How to cite this article.
Granulomatose eosinofílica com poliangiite (Síndrome de Churg-Strauss)
Churg-Strauss syndrome is characterized by asthma, eosinophilia and various degrees of systemic vasculitis. The most severe forms of the disease, presenting cardiac, gastrointestinal, central nervous system and renal involvement, require cyclophosphamide therapy. Churg J, Strauss L. Allergic granulomatosis, allergic angiitis, and periarteritis nodosa. Am J Pathol.
Churg-Strauss syndrome is a rare systemic disease primarily characterized by hypereosinophilia, asthma and vasculitis. The lung is the organ most frequently involved. In the present report, the authors describe a relatively rare finding in this disease - the presence of a pulmonary nodule -, while recalling the main radiological findings and the most relevant differential diagnoses. Radiol Bras.
Back to Summary. Asthma and Churg-Strauss syndrome. J Bras Pneumol. In the s, Wegener's granulomatosis, a necrotizing vasculitis that affects the small blood vessels and is accompanied by impaired renal function, was discovered.