The liquid suspension time-kill test is excellent for disinfectant product developers because it is a fast, relatively inexpensive, and reproducible way to measure the biocidal potential of a liquid antimicrobial formulation. It consists of directly inoculating a liquid test substance with a high concentration of test microorganisms and then determining the percentage killed over time. At Microchem Laboratory, we are proud of our tradition of collaborative, productive, antimicrobial research and development. The suspension-based time-kill test is just one of many tools we use to help companies develop disinfectants and other antimicrobial products. Breadcrumb Home.
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Ask for rush delivery. Most backordered items can be rushed in from the publisher in as little as 24 hours. Some rush fees may apply. Add to Cart. View Full Details and Buy. Complementary Documents and Links:. This guide covers an example of a method that measures the changes in a population of aerobic microorganisms within a specified sampling time when antimicrobial test materials are present.
Several options for organism selection and growth, inoculum preparation, sampling times and temperatures are provided. When the technique is performed as a specific test method, it is critical that the above mentioned variables have been standardized.
Antimicrobial activity of specific materials, as measured by this technique, may vary significantly depending on variables selected. It is important to understand the limitations of in vitro tests, especially comparisons of results from tests performed with different parameters.
As an example, test results of microorganisms requiring growth supplements or special incubation conditions may not be directly comparable to organisms evaluated without those stated conditions. Knowledge of microbiological techniques is required for this procedure. The values stated in SI units are to be regarded as standard. No other units of measurement are included in this standard. This standard does not purport to address all of the safety concerns, if any, associated with its use.
It is the responsibility of the user of this standard to establish appropriate safety and health practices and determine the applicability of regulatory requirements prior to use. Browse Publishers. Top Sellers. My Account. Corporate Sustainability. Investor Relations. All Rights Reserved. Update Cart. Create New Account.
ASTM E2315 - Liquid Suspension Time-Kill Test
Active view current version of standard. Other Historical Standards. More E Several options for organism selection and growth, inoculum preparation, sampling times and temperatures are provided. When the basic technique is performed as a specific test method it is critical when evaluating the results to ensure that such variables have been standardized. Antimicrobial activity of specific materials, as measured by this technique, may vary significantly on variables selected.
The Liquid Suspension Time-Kill begins with the direct inoculation of a volume of the disinfectant in question with a specified representative organism. After a specified contact time the system is neutralized and the presence of microorganisms is monitored and quantified following a period of incubation. The microbial growth is compared to that of an untested enumeration control to determine the total reduction. With Microchem Laboratory a Liquid Suspension Time-Kill test procedure is highly versatile and catered directly to the study sponsor's needs. For example, to zero in on the minimum effective contact time for the disinfectant at tested conditions, multiple contact times can be used.